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Articles + Publications July 17, 2025
In the midst of shifting political headwinds and a tight funding market, many life sciences companies are considering their M&A exit. Potential acquirers (both strategic and private equity) have plenty of dry powder and are ready to drive transactions to the finish line. However, in positioning themselves as acquisition targets, life sciences companies must carefully consider the impact of their existing strategic collaborations on any potential deal. Often, an existing collaboration can be a strong driver of M&A interest and value, but these relationships can also introduce complexities — making alignment with collaboration partners crucial for a seamless transaction.
Potential Restrictions on Sale
When a life sciences company becomes the target of a potential acquisition, it must consider whether any of its collaboration partners have direct or indirect influence over the transaction. Often, collaboration partners — entities or organizations that work jointly with the target company on specific projects, programs, or initiatives — enter into the collaboration as a preview of the target company, with the intent of later acquiring the subject asset or even the target company if the collaboration is successful. As a result, companies may first want to talk with their collaboration partners about their interest in making the acquisition. This can be challenging for a company that has multiple collaboration partners or that wants to test the market for an acquisition without signaling to its partners that a deal may be in the offing.
If the collaboration partner is not a potential acquirer (or is one of several potential acquirers), the target company will need to look at the underlying collaboration agreements for restrictions on any potential sale to a third party. In particular, lock-up periods and consent requirements may be stipulated in existing collaboration agreements. Lock-up periods may restrict the sale of the target company for a specified duration, while consent requirements may necessitate obtaining approval from the collaboration partner before proceeding with the acquisition. Additionally, the acquisition could trigger other penalties or give the collaboration partner a right to terminate the collaboration arrangement. This could be a particular concern if the collaboration is a significant factor in the acquiring the company’s interest in the target.
Collaboration agreements may also grant the collaboration partner representation on the target company’s board of directors, potentially influencing the acquisition process through voting rights or other abilities to affect significant transaction decisions.
Therefore, it is essential for the target company to thoroughly review its collaboration agreements to assess the extent of the collaboration partner’s influence on the potential transaction and to identify potential sale restrictions. If such restrictions exist, the target company should consider proactively negotiating with the collaboration partner to obtain consents, waive penalties, or determine whether the arrangement will remain post-closing. It is also important to engage collaboration partners in open communication to ensure interests are aligned.
Confidentiality and Information Sharing
To ensure a collaboration partner is aligned with a potential acquisition, information must inevitably be shared. Relevant information should only be shared on a limited, strategic basis, and the target company must carefully consider its confidentiality obligations to both its collaboration partner and the potential acquirer.
It is not uncommon for the potential transaction and related discussions to be considered confidential information of the acquirer. Therefore, when negotiating initial confidentiality agreements and the letter of intent with the acquirer, the target company should evaluate if there are any collaboration partners that are essential to the transaction outcome and reach an agreement with the acquirer as to how much information can be shared with those partners.
Similarly, during the due diligence process, the potential acquirer will assess the target company’s operations, financials, and IP and may also seek information about the collaboration — which is likely confidential under the collaboration agreement. Therefore, it is essential to work closely with collaboration partners to ensure they are aligned with respect to the transaction and are willing to permit such disclosures.
IP Considerations and Valuation
Collaborations bring strategic value, such as providing access to new markets, technologies, or expertise, and they almost always involve the creation and sharing of IP. Because IP is typically the key asset for a life sciences company, the existence of a strategic collaboration can significantly impact the valuation of a target company, and is frequently a decisive factor in an acquirer’s decision to proceed with a transaction. Therefore, understanding the potential positive and negative impacts of the collaboration on the target company’s IP rights and overall valuation is essential for negotiating a fair acquisition price and ensuring the deal closes.
Since IP is often the value-driver of a life sciences transaction, it can create the most opportunity for valuation issues and deal roadblocks. The target company must understand its ownership and use rights with respect to IP created and shared in its existing collaborations, and how that IP may be later accessed and used by the acquirer. For example, the target company may have exclusive rights to certain collaboration IP, but the collaboration partner may be the ultimate owner. This may not affect deal value if the exclusive rights are sufficient for the strategic goals of the acquirer, but to avoid deal roadblocks, the target company will need to give the acquirer assurances that those assets will continue to be available post-closing.
Licenses granted to or obtained from the collaboration partner, and related royalties and milestone payments, can also affect the target company’s operations and revenue streams. It is important to review these licenses and assess their continuity and related economics post-acquisition. Discussions with the collaboration partner to ensure the seamless transfer or continuation of licenses can prevent disruptions and preserve the value of the target company’s IP portfolio.
Conclusion
Preparing for an acquisition while managing an existing collaboration requires careful planning and strategic decision-making. By addressing potential restrictions on sale, maintaining confidentiality, and considering IP implications, life sciences companies can ensure a smooth and successful acquisition transaction.
Sponsored Events
2026 AUTM Annual Meeting
February 8 – 11, 2026
Seattle, WA
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February 4 – 5, 2026
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777 Casino Dr, Pittsburgh, PA 15212
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Miami Beach, FL
Leading the energy evolution.
Learn more
From compliance to the courtroom, we have you covered.
Learn more
Helping you focus on what matters – improving human health.
Learn more
Trusted advisors to leading insurers for 100+ years.
Learn more
Unlocking value in the middle market and beyond.
Learn more
Full-service legal advice from coast to coast.
Learn more
Applying radical applications of common sense
Explore More
Our standard-setting client experience program.
Explore more
Delivering life-changing help to those most in need.
Explore More
Our firm’s greatest asset is our people.
Explore More
Market-leading eDiscovery and data management services.
Explore more
The Pepper Center for Public Services
Explore more
Strategies helps businesses and individuals solve the complexities of dealing with the government at every level. Our team of specialists concentrate exclusively on government affairs, representing clients nationwide who need assistance with public policy, advocacy, and government relations strategies.
This unique program provides innovative and affordable opportunities to startups and early-stage emerging companies with a solid technology or scientific foundation. We help companies that have a quality management team in place and do not have other significant legal representation.
eMerge’s lawyers and technologists work together to deliver strategic end-to-end eDiscovery and data management solutions for litigation, investigations, due diligence, and compliance matters. We help clients discover the information necessary to resolve disputes, respond to investigations, conduct due diligence, and comply with legal requirements.
Stay ahead of the curve and in touch with our latest thinking on the issues that are top of mind across our practices and industry sectors.
Change happens fast in today’s turbulent world. Stay on top of the latest with our industry-specific channels.
Take a closer look at how we partner with clients to help them realize their goals.